Download Aplastic Anemia and Other Bone Marrow Failure Syndromes by Mehdi Tavassoli (auth.), Nasrollah T. Shahidi (eds.) PDF

By Mehdi Tavassoli (auth.), Nasrollah T. Shahidi (eds.)

During the previous decade, there were various direct and oblique medical contributions to either the etiology and remedy of aplastic anemia and similar bone marrow failure syndromes. medical observations, resembling autologous bone marrow restoration after conditioning with immunosup­ pressive brokers for bone marrow transplantation; failure to accomplish en­ graftment in a few exact twins with out earlier immunosuppressive ther­ apy; and hematologic reaction to immunosuppressive brokers, have ended in the concept that of immune-mediated etiology of obtained aplastic anemia. any such thought used to be extra reinforced through laboratory findings, implicat­ ing the function of activated cytotoxic T lymphocytes and irregular produc­ tion of inhibitory lymphokines. The immunologic mechanisms can also observe to the idiosyncratic bone marrow aplasias linked to medications, poisonous chemical compounds, and viruses. those brokers could adjust basic mobile recog­ nition websites by means of interacting with mobile elements and bring about lack of self tolerance. Immunologic mechanisms have lengthy been endorsed in lots of different organ disasters, and the hemopoietic organ is not any exception. it truly is of curiosity that parallel medical and laboratory investigations in juvenile diabetes mellitus sort I and in rodent versions of this ailment have yielded effects suitable with an identical pathogenic mechanisms. The infiltration of pancreatic islets through activated T lymphocytes, sensible and morphological adjustments of islet cells upon incubation with lymphokines equivalent to gamma interferon and tumor necrosis issue, and medical reaction to cyclosporine are a couple of examples.

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Additional resources for Aplastic Anemia and Other Bone Marrow Failure Syndromes

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20 Mehdi Tavassoli 49. Golde DW, Cline MJ. Identification of the colony-stimulating cell in human peripheral blood. J Clin Invest 1972; 51 :2981- 2983. 50. Zuckerman KS. Human erythroid burst forming units. Growth in vitro is dependent on monocytes, but not T lymphocytes. J Clin Invest 1981; 67:702-709. 51. Reid CPL, Batista LC, Chanarin I. Erythroid colony growth in vitro from human peripheral blood null cells: Evidence for regulation by T -lymphocytes and monocytes. Br J Haematol 1981; 48:155-164.

Mangan KF, Chikkappa G, Sieler LZ et al. Regulation of human blood erythroid burst-forming unit (BFU-E) proliferation by T-lymphocyte subpopulation defined by Fc receptors and monoclonal antibodies. Blood 1982; 59:990-996. Chervenick PA, LoBuglio AF. Human blood monocytes: stimulators of granulocyte and mononuclear colony formation in vitro. Science 1972; 178:164-166. 20 Mehdi Tavassoli 49. Golde DW, Cline MJ. Identification of the colony-stimulating cell in human peripheral blood. J Clin Invest 1972; 51 :2981- 2983.

Nagao T, Mauer AM. Concordance for drug-induced aplastic anemia in identical twins. N Engl J Med 1969; 281:7 - 11. 16. Hodgkinson R. The chloramphenicol-hepatitis-aplastic anaemia syndrome. Med J. Aust 1973; 1:939. 17. Casale TB, Macher AM, et al. Complete hematologic and hepatic recovery in a patient with chloramphenicol hepatitis-pancytopenia syndrome. J Pediatr 1982; 101:1025. 18. Yunis AA. Mechanisms underlying marrow toxicity from chloramphenicol and thiamphenicol. In: Silber R, LoBue J, et al, eds.

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